99mTc-MIBI Uptake and Multidrug Resistance.
نویسندگان
چکیده
منابع مشابه
Negative 99mTc-MIBI uptake in a parathyroid carcinoma: A case report
A 34 year old woman with malaise, polyuria and nocturia as well as nausea and vomiting referred to perform a thyroid scan due to right thyroid lobe mass. The scan showed a cold nodule in the right thyroid lobe. Serum calcium of 16.9, serum phosphorus of 1.8 and PTH of 1156 were noticed in laboratory tests. Parathyroid scan with 99mTc-MIBI showed no abnormal tracer activity in the nec...
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UNLABELLED The aim of this study was to assess the value of 99mTc-hexakis2-methoxyisobutylisonitrile (MIBI) scintigraphy in patients with clinical and radiologic features of primary or metastatic musculoskeletal tumors. METHODS The scintigraphic findings for 84 patients were compared with the surgical and histologic findings. Each patient underwent three-phase bone scanning with 99mTc-methyle...
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This case shows the improvement promoted by cardiac resynchronization therapy (CRT) on myocardial perfusion and left ventricular (LV) performance assessed by gated myocardial perfusion scintigraphy. The patient had idiopathic dilated cardiomyopathy, left bundle branch block and severe heart failure despite optimized medical treatment. After CRT, clinical improvement, QRS reduction and improveme...
متن کاملAbsent radiotracer uptake in thyroid gland in parathyroid scintigraphy with 99mTc-MIBI: A case report
Localization of 99mTc- hexakis-2-methoxyisobutylisonitrile (99mTc-MIBI) by parathyroid adenomas is well known, and this warrants MIBI scan to evaluate suspected parathyroid adenoma in primary hyperparathyroidism. Typically, the radionuclide concentrates in both the thyroid gland and parathyroid adenoma in early images, and later on delayed images washes out slowly from the...
متن کاملBromocriptine enhances the uptake of 99mTc-MIBI in patients with hepatocellular carcinoma
(99m)Tc-methoxyisobutyl isonitrile (MIBI) is a suitable transport substrate for the multidrug resistance gene product P-glycoprotein (P-gp) and widely used for tumor imaging. Bromocriptine has been shown to inhibit the ATPase activity and the function of P-gp. We hypothesized that bromocriptine could promote the accumulation of MIBI by inhibiting P-gp activities, a feature that can be taken adv...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1996
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.45.661